Under the EU REACH regulation (EC No. 1907/2006) it is required for substances which are produced and/or imported in tonnages at or above 10 tons per year and which have been identified as being "hazardous" (according to 67/548/EEC), to develop so-called "exposure scenarios". An integral part of these exposure scenarios is the estimation of exposure for all relevant routes. For workers, the inhalation and dermal exposure route are commonly assumed to be relevant.
To assess occupational exposure, the available ECHA guidance foresees a "tiered approach". For the 1st tier, it is proposed to use so-called "screening tools". These tools provide conservative estimates of exposure and are meant to identify scenarios for which higher tier assessments are needed (tiered tools or measurements).
On behalf of EUROMETAUX, EBRC has developed a tool for the estimation and assessment of substance exposure (MEASE version 1) which combined approaches from the EASE expert system, from the ECETOC TRA tool and from the health risk assessment guidance for metals (HERAG). It aimed at providing a 1st tier screening tool for the estimation of occupational inhalation and dermal exposure to metals and inorganic substances.
MEASE (version 1.02.01) http://www.ebrc.de/mease.html has been broadly used by the metals’ industry for chemical safety assessments in REACH registration dossiers during the last years.
Continuous updating of MEASE on regular basis was foreseen after publishing the first version of MEASE in order to reflect comments from users of the tool received, to provide reasonable exposure estimates reflecting up-to-date monitoring data and to also reflect updates of ECHA guidance, and a link with ECHA’s CHEmical Safety Assessment and Reporting tool (Chesar) which aims at facilitating the drafting of ES and CSR has been developed. But also, MEASE 1.0 has been included in the ETEAM project (Evaluation of Tier 1 Exposure Assessment Models under Reach), a project validating and comparing the different REACH Tier 1 exposure assessment models in terms of their determinants, scope of application, functionality and user-friendliness.
To reflect the outcomes of the ETEAM project, increase user friendliness and to enable functional interactions with Chesar, MEASE needs now to undergo substantial revision and several additional features need to be implemented. MEASE 2 will be developed as a standalone-software to address the above aspects.
MEASE 2 is coming soon
Last page update: 1 October 2018